Host: Rabbit
Target Protein: 14-3-3 Alpha + Beta + Gamma + Delta + Epsilon
IR: Immunogen Range:174-245/245
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 7529
Swiss Prot: P31946
Source: KLH conjugated synthetic peptide derived from human 14-3-3:174-245/245
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca (2+)/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family.
This antibody is reactive with 14-3-3 Alpha, Beta, Gamma, Delta, Epsilon.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg /test.
Cross Reactive Species: Human,Mouse,Rat (predicted: Sheep,Fruit Fly,yeast,)
For research use only. Not intended for diagnostic or therapeutic use.