Host: Rabbit

Target Protein: KMT2D/ALL1

IR: Immunogen Range:1301-1400/5537

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8085

Swiss Prot: O14686

Source: KLH conjugated synthetic peptide derived from human KMT2D/ALL1:1301-1400/5537 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]