Host: Rabbit
Target Protein: KPNA6
IR: Immunogen Range:101-200/536
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 23633
Swiss Prot: O60684
Source: KLH conjugated synthetic peptide derived from human KPNA6:101-200/536
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, Flow-Cyt=1ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse (predicted: Rat,Chicken,Pig,Cow,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.