Host: Rabbit
Target Protein: RNF109/TRIM56
IR: Immunogen Range:651-755/755
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 81844
Swiss Prot: Q9BRZ2
Source: KLH conjugated synthetic peptide derived from human RNF109/TRIM56:651-755/755
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Rat (predicted: Human,Mouse,Dog,Cow,Horse,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.