Host: Rabbit
Target Protein: HSCB
IR: Immunogen Range:101-200/235
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 150274
Swiss Prot: Q8IWL3
Source: KLH conjugated synthetic peptide derived from human HSCB:101-200/235
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: HscB is a 235 amino acid mitochondrial protein that functions as a co-chaperone in iron-sulfur cluster formation. Highly expressed in heart, liver and muscle, and belonging to the HscB family, HscB exists as a L-shaped crystal structure resembling E. coli HscB. Human HscB contains an N-terminal mitochondrial targeting signal followed by a J-domain and short loop. The C-terminal domain folds into a compact 3-helix bundle and likely mediates specific interactions with IscU. Containing six exons and five introns, the gene encoding HscB maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.
Size: 100ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.