Host: Rabbit

Target Protein: Histone H2B (acetyl K12)

IR: Immunogen Range:AP(Acetyl–K)KG

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 54145

Swiss Prot: Q5QNW6

Source: KLH conjugated Synthesised acetylpeptide derived from human Histone H2B around the acetylation site of acetyl Lys12:AP(Acetyl–K)KG 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2B family and is found in a histone cluster on chromosome 1. [provided by RefSeq, Jan 2013]