Host: Rabbit
Target Protein: SIDT2
IR: Immunogen Range:201-300/832
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 51092
Swiss Prot: Q8NBJ9
Source:
KLH conjugated synthetic peptide derived from human SIDT2:201-300/832
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.