Host: Rabbit

Target Protein: SPATA5

IR: Immunogen Range:801-893/893

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 166378

Swiss Prot: Q8NB90

Source: KLH conjugated synthetic peptide derived from human SPATA5:801-893/893 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: SPATA5 is an 893 amino acid protein that localizes to cytoplasm and mitochondrion, and may be involved in morphological and functional mitochondrial transformations during spermatogenesis. Existing as three alternatively spliced isoforms, SPATA5 belongs to the AAA ATPase family and the AFG2 subfamily. The gene that encodes SPATA5 consists of more than 396,000 bases and maps to human chromosome 4q28.1. Housing nearly 900 genes, chromosome 4 represents approximately 6% of the human genome and is associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.