Host: Rabbit

Target Protein: MPP8/MPHOSPH8

IR: Immunogen Range:601-700/860

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 54737

Swiss Prot: Q99549

Source: KLH conjugated synthetic peptide derived from human MPHOSPH8:601-700/860 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: MPHOSPH8 is a 860 amino acid nuclear protein that is phosphorylated in the M (mitotic) phase of the cell cycle. MPHOSPH8 contains four ANK repeats, motifs that are typically found in transcriptional regulators and cell cycle proteins and may be involved in protein-protein binding. Due to evidence suggesting that MPHOSPH8 forms a complex with Muskelin and Ran BP-M, a GTPase implicated in a diverse array of cellular processes, it may play a role in the Ran GTPase cycle. The gene encoding MPHOSPH8 resides on chromosome 13. There are two isoforms of MPHOSPH8 that are produced as a result of alternative splicing events.