Host: Rabbit

Target Protein: HLCS

IR: Immunogen Range:221-320/726

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3141

Swiss Prot: P50747

Source: KLH conjugated synthetic peptide derived from human HLCS:221-320/726 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011]