Host: Rabbit

Target Protein: phospho-IKB alpha (Ser32)

IR: Immunogen Range:D(p-S)GL

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4792

Swiss Prot: P25963

Source: KLH conjugated Synthesised phosphopeptide derived from human IKB alpha around the phosphorylation site of Ser32:D(p-S)GL 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]