Host: Rabbit

Target Protein: TDO2/tryptophan 2,3-dioxygenase

IR: Immunogen Range:301-406/406

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6999

Swiss Prot: P48775

Source: KLH conjugated synthetic peptide derived from human TDO2:301-406/406 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]