Host: Rabbit
Target Protein: TDO2/tryptophan 2,3-dioxygenase
IR: Immunogen Range:301-406/406
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6999
Swiss Prot: P48775
Source: KLH conjugated synthetic peptide derived from human TDO2:301-406/406
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Dog,Horse)
For research use only. Not intended for diagnostic or therapeutic use.