Host: Rabbit

Target Protein: MCF2L2

IR: Immunogen Range:741-840/1114

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23101

Swiss Prot: Q86YR7

Source: KLH conjugated synthetic peptide derived from human MCF2L2:741-840/1114 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: MCF2L2 is a 1,114 amino acid protein that contains one spectrin repeat, one PH domain, one DH domain and one CRAL-TRIO domain. Expressed at high levels in brain and also present in testis and pancreas, MCF2L2 is thought to function as a GEF, catalyzing the activation of target GTPases. Variations in the gene encoding MCF2L2 may be associated with an increased susceptibility to type 2 diabetes. Multiple isoforms of MCF2L2 exist due to alternative splicing events.