Host: Rabbit

Target Protein: STAC

IR: Immunogen Range:21-120/402

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6769

Swiss Prot: Q99469

Source: KLH conjugated synthetic peptide derived from human STAC:21-120/402 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: STAC is a 402 amino acid protein that contains one SH3 (Src homology 3) domain and one cysteine-rich domain (CRD). Expressed in brain, STAC is a neuron-specific protein that localizes to the cytoplasm and, based on the frequent involvement of SH3 and CRD domains in signal transduction, is believed to play a role in neuron-specific signal transduction. In addition, STAC may be involved in protecting cells from apoptosis. Due to its neuron-specific expression and putative role in signal transduction, STAC may be implicated in a variety of hereditary neurological diseases.