Host: Rabbit
Target Protein: MICALL1/MIRab13
IR: Immunogen Range:401-500/863
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 85377
Swiss Prot: Q8N3F8
Source: KLH conjugated synthetic peptide derived from human MICALL1/MIRab13:401-500/863
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: MIRAB13 is an 863 amino acid cytoplasmic protein belonging to the MICAL family that contains one CH (calponin-homology) domain, one LIM zinc-binding domain and two unique asparagine-proline-phenylalanine motifs, which are known to interact with EH-domains. Considered a cytoskeletal regulator, MIRAB13 associates with Rab 13, a tight junction protein, as well as EHD, a key regulator of ligand-induced endocytosis and recycling. MIRAB13 is encoded by a gene located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.