Host: Rabbit

Target Protein: phospho-RUNX1 (Ser276)

IR: Immunogen Range:PI(p-S)PG

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 861

Swiss Prot: Q01196

Source: KLH conjugated synthesised phosphopeptide derived from human RUNX1 around the phosphorylation site of Ser276:PI(p-S)PG 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]