Host: Rabbit

Target Protein: MYL12B

IR: Immunogen Range:2-80/172

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 103910

Swiss Prot: O14950

Source: KLH conjugated synthetic peptide derived from human MYL12B:2-80/172 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008]