Host: Rabbit
Target Protein: NEK10
IR: Immunogen Range:51-150/1172
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 152110
Swiss Prot: Q6ZWH5
Source: KLH conjugated synthetic peptide derived from human NEK10:51-150/1172
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
Nek10 is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.
Predicted molecular weight: 55 kDa for Isoform 5 (and 133 kDa for Isoform 1).
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.