Host: Rabbit

Target Protein: NRN1L

IR: Immunogen Range:81-165/165

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 123904

Swiss Prot: Q496H8

Source: KLH conjugated synthetic peptide derived from human NRN1L:81-165/165 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: NRN1L is a 165 amino acid membrane protein that belongs to the neuritin family. The gene that encodes NRN1L consists of approximately 1,495 bases and maps to human chromosome 16q22.1. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2 gene, both of which are located on chromosome 16, results in Rubinstein-Taybi syndrome and Crohn's disease, respectively.