Host: Rabbit

Target Protein: EST1A

IR: Immunogen Range:1-100/1419

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23293

Swiss Prot: Q86US8

Source: KLH conjugated synthetic peptide derived from human EST1A:1-100/1419 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014]