Host: Rabbit

Target Protein: NSUN2

IR: Immunogen Range:101-200/767

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 54888

Swiss Prot: Q08J23

Source: KLH conjugated synthetic peptide derived from human NSUN2:101-200/767 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]