Host: Rabbit

Target Protein: CD2BP1/PSTPIP1

IR: Immunogen Range:101-200/416

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 9051

Swiss Prot: O43586

Source: KLH conjugated synthetic peptide derived from human CD2BP1/PSTPIP1:101-200/416 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq, Jul 2008]