Host: Rabbit

Target Protein: SCRIBBLE

IR: Immunogen Range:1-100/1630

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23513

Swiss Prot: Q14160

Source: KLH conjugated synthetic peptide derived from human SCRIBBLE:1-100/1630 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]