Host: Rabbit
Target Protein: SEC63
IR: Immunogen Range:351-250/760
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 11231
Swiss Prot: Q9UGP8
Source:
KLH conjugated synthetic peptide derived from human SEC63:351-250/760
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Size: 200ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Chicken,Pig,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.