Host: Rabbit

Target Protein: GRTP1

IR: Immunogen Range:231-336/336

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 79774

Swiss Prot: Q5TC63

Source: KLH conjugated synthetic peptide derived from human GRTP1:231-336/336 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: GRTP1 is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events.