Host: Rabbit
Target Protein: SF3B4
IR: Immunogen Range:2-100/424
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 10262
Swiss Prot: Q15427
Source: KLH conjugated synthetic peptide derived from human SF3B4:2-100/424
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
Cross Reactive Species: Rat (predicted: Human,Mouse,Saccharomyces cerevisiae, Fruit fly (Drosophila melanogaster)
For research use only. Not intended for diagnostic or therapeutic use.