Host: Rabbit

Target Protein: phospho-SH3BP2 (Ser427)

IR: Immunogen Range:SF(p-S)FE

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6452

Swiss Prot: P78314

Source: KLH conjugated synthesised phosphopeptide derived from human SH3BP2 around the phosphorylation site of Ser427:SF(p-S)FE 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]