Host: Rabbit
Target Protein: PDGFRA
IR: Immunogen Range:321-420/1089
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5156
Swiss Prot: P16234
Source:
KLH conjugated synthetic peptide derived from human PDGFRA:321-420/1089
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Dog,Cow,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.