Host: Rabbit

Target Protein: phospho-Smad3 (Thr179)

IR: Immunogen Range:PE(p-T)PP

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4088

Swiss Prot: P84022

Source: KLH conjugated synthesised phosphopeptide derived from human Smad3 around the phosphorylation site of Thr179:PE(p-T)PP 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]