Host: Rabbit

Target Protein: Phospho-NFKB2 (Ser866+Ser870)

IR: Immunogen Range:ED(p-S)AYG(p-S)QS

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4791

Swiss Prot: Q00653

Source: KLH conjugated synthesised phosphopeptide derived from human NFKB2 around the phosphorylation site of Ser866 + Ser870:ED(p-S)AYG(p-S)QS 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]