Host: Rabbit

Target Protein: phospho-Survivin (Thr34)

IR: Immunogen Range:AC(p-T)PE

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 332

Swiss Prot: O15392

Source: KLH conjugated synthesised phosphopeptide derived from human Survivin around the phosphorylation site of Thr34:AC(p-T)PE 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]