Host: Rabbit
Target Protein: Ras and Rab interactor 2
IR: Immunogen Range:201-300/895
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 54453
Swiss Prot: Q8WYP3
Source: KLH conjugated synthetic peptide derived from human Ras and Rab interactor 2:201-300/895
Purification: affinity purified by Protein A
Storage: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
Cross Reactive Species: (predicted: Human,Mouse,Rat,Dog,Cow,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.