Host: Rabbit
Target Protein: TRAF4
IR: Immunogen Range:1-100/470
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 9618
Swiss Prot: Q9BUZ4
Source: KLH conjugated synthetic peptide derived from human TRAF4:1-100/470
Purification: affinity purified by Protein A
Storage: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008].
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse (predicted: Sheep,Rabbit,Human)
For research use only. Not intended for diagnostic or therapeutic use.