Host: Rabbit
Target Protein: phospho-TRAP220 (Thr1457)
IR: Immunogen Range:AY(p-T)PQ
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5469
Swiss Prot: Q15648
Source: KLH conjugated Synthesised phosphopeptide derived from human TRAP220 around the phosphorylation site of Thr1457:AY(p-T)PQ
Purification: affinity purified by Protein A
Storage: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.
Size: 200ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.