Host: Rabbit
Target Protein: Transition Protein 1
IR: Immunogen Range:201-300/499
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 14852
Swiss Prot: P15170
Source: KLH conjugated synthetic peptide derived from mouse Transition Protein 1:201-300/499
Purification: affinity purified by Protein A
Storage: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.