Host: Rabbit

Target Protein: phospho-MYL12B (Thr19 + Ser20)

IR: Immunogen Range:RA(p-T)(p-S)N

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 103910

Swiss Prot: O14950

Source: KLH conjugated synthesised phosphopeptide derived from human Mylc2b around the phosphorylation site of Thr19 + Ser20:RA(p-T)(p-S)N 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008]