Host: Rabbit
Target Protein: CCR-2
IR: Immunogen Range:301-373/373
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 12772
Swiss Prot: P51683
Source:
KLH conjugated synthetic peptide derived from mouse CCR-2:301-373/373
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, Flow-Cyt=1ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human
For research use only. Not intended for diagnostic or therapeutic use.