Host: Rabbit

Target Protein: Topoisomerase I

IR: Immunogen Range:401-500/765

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7150

Swiss Prot: P11387

Source: KLH conjugated synthetic peptide derived from human Topoisomerase I:401-500/765 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]