Host: Rabbit

Target Protein: SREBP2

IR: Immunogen Range:951-1141/1141

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6721

Swiss Prot: Q12772

Source: KLH conjugated synthetic peptide derived from human SREBP-2:951-1141/1141 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.