Host: Mouse
Target Protein: EIF4EBP1
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: IgG1
Entrez Gene: 1978
Swiss Prot: Q13541
Source: Recombinant human EIF4EBP1:
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.