Host: Mouse
Target Protein: Cyclophilin B(Loading Control)
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 5479
Swiss Prot: P23284
Source: KLH conjugated synthetic peptide derived from human Cyclophilin B:
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:100-500
Cross Reactive Species: Rat,Mouse,Human
For research use only. Not intended for diagnostic or therapeutic use.