Host: Rabbit
Target Protein: NALP3/CIAS1
IR: Immunogen Range:501-600/1036
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 114548
Swiss Prot: Q96P20
Source: KLH conjugated synthetic peptide derived from human NALP3/CIAS1:501-600/1036
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
Size: 100ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat,Rabbit (predicted: Dog,Pig,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.