Host: Mouse
Target Protein: BCL-6
IR: Immunogen Range:676-704/706
Clonality: Monoclonal
Isotype: IgG1
Entrez Gene: 604
Swiss Prot: P41182
Source: KLH conjugated synthetic peptide derived from human BCL-6:676-704/706
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Size: 50ul
Concentration: 1mg/1ml
Applications: WB=1:500-5000, IF=1:20-200, ELISA=1:500-5000
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.