Host: Rabbit

Target Protein: Islet-1

IR: Immunogen Range:51-150/349

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3670

Swiss Prot: P61371

Source: KLH conjugated synthetic peptide derived from human Islet-1:51-150/349 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008].