Host: Mouse
Target Protein: human CD4
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: Mouse IgG2b
Entrez Gene: 920
Swiss Prot: P01730
Source: KLH conjugated synthetic peptide derived from human CD4:
Purification: Affinity purified by Protein G
Storage: 0.01M TBS(pH=7.4) Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
Size: 100ug
Concentration: 1mg/ml
Applications: Flow-Cyt=2ug/Test
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.