Host: Rabbit
Target Protein: MRP1/ABCC1
IR: Immunogen Range:1131-1230/1531
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4363
Swiss Prot: P33527
Source:
KLH conjugated synthetic peptide derived from human MRP1/ABCC1:1131-1230/1531
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Human,Rat,Chicken,Dog,Cow,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.