bsm-33443M [Primary Antibody]
Mouse  Anti-Ubiquitin  Monoclonal Antibody
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Host: Mouse

Target Protein: Ubiquitin

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 7314

Swiss Prot: P0CG48

Source: KLH conjugated synthetic peptide derived from human Ubiquitin: 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Size: 50ul

Concentration: 1mg/ml

Applications: IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500

Cross Reactive Species: Mouse (predicted: Human,Rat)

For research use only. Not intended for diagnostic or therapeutic use.

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