Host: Rabbit
Target Protein: HLA-DR/HLA DRB1
IR: Immunogen Range:26-100/224
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3122
Swiss Prot: P01903
Source:
KLH conjugated synthetic peptide derived from human HLA-DR/HLA DRB1 :26-100/224
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.