Host: Rabbit

Target Protein: Phospho-TrkB (Tyr817)

IR: Immunogen Range:PV(p-Y)LD

Clonality:

Isotype: IgG

Entrez Gene: 4915

Swiss Prot: Q16620

Source: KLH conjugated Synthesised phosphopeptide derived from human NTRK2 around the phosphorylation site of Tyr817:PV(p-Y)LD 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].